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Lung exposure to noxious agents, including smoke, silica dust, nanosized silica, or carbon-derived nanomaterials can trigger mucosal toll-like receptors (TLRs) that activate Ca 2+ -mediated PADs, but also antigen-presenting cells (APCs), such as classical dendritic cells (DCs) and B cells

A single-phase gel consists of organic macromolecules distributed uniformly throughout a liquid in such a manner that no apparent boundaries exist between the dispersed macromolecules and the liquid

These are not minor differences of degree

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